A structural perspective on Mediator function
نویسندگان
چکیده
منابع مشابه
A structural perspective on Mediator function.
Gene transcription by RNA polymerase II requires the multiprotein coactivator complex Mediator. Mediator was identified two decades ago, but its molecular mechanisms remain poorly understood, because structural studies are hampered by its large size, modularity, and flexibility. Here we collect all available structural data on Mediator and discuss their functional implications. Progress was mad...
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ژورنال
عنوان ژورنال: Current Opinion in Cell Biology
سال: 2012
ISSN: 0955-0674
DOI: 10.1016/j.ceb.2012.01.007